Light-Chain Immunoglobulins

《英文msh詞典》Light-Chain Immunoglobulins
[入口詞] Light-Chain Immunoglobulins
[主題詞] Immunoglobulins,Light-Chain
[中文釋義] 輕鏈免疫球蛋白類
[英文釋義] Polypeptide chains,consisting of 211 to 217 amino acid residues,isolated from immunoglobulins and having a molecular weight of approximately 22 kD. There are two major types of light chains,kappa and lambda. In man they are found in a ratio of 60% to 40%,respectively. Both chains consist of linear repeating,similar,but not identical,segments of about 110 amino acid residues. In each segment a disulfide bond establishes a tightly folded approximately 60-membered loop or domain. Adjacent domains are linked by less tightly folded regions. Both light chains contain two such domains. Two light and two heavy chains make one immunoglobulin molecule,but both light chains in one Ig are of the same type.